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OCR: hal in Levels of fasting plasma glucose are nor sting adults with GH deficiency, but those of f icularly in insulin and C-peptide are increased, par a state of patients who are overweight, suggesting n and insulin resistance. Plasma glucose, insu ement C-peptide levels rise following GH repla Iths therapy and remain elevated after six m gressively, The insulin: C-peptide ratio increases pr tory thus suggesting an alteration in postsecr le insulin metabolism, possibly related to n HbA1 reduction in abdominal fat. No changes have been noted